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KMID : 1143520230110010107
Journal of Korean Society of Oral Health Science
2023 Volume.11 No. 1 p.107 ~ p.113
Antibacterial Activity of Lemongrass Oil and Lemongrass Ethanol Extract Against Porphyromonas gingivalis
Yoon Hyun-Seo

Park Chung-Mu
Abstract
Objectives: This study analyzed the antibacterial effects of LGEE and LGEO against P. gingivalis, thus the potential utility was evaluated as the functional materials for oral healthcare.

Methods: Nitric oxide (NO) assay and cytotoxicity were analyzed by the Griess reaction and WST-1 assay, respectively. Antibacterial activity against P. gingivalis was evaluated by disk diffusion method and proliferation inhibition assay.

Results: LGEO and LGEE significantly inhibited NO production as well as the proliferation of P. gingivalis in a dose dependent manner.

Conclusions: LGEO and LGEE inhibited potently NO production and P. gingivalis proliferation, which means they could be used as a numerous lines of functional materials for improving oral health.
KEYWORD
Antibacterial, Lemon grass oil, Natural extracts, P.gingivalis
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